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| 2. |  | ODRIOZOLA, E.R.; RODRÍGUEZ, A.M.; MICHELOUD, J.F.; CANTÓN, G.J.; CAFFARENA, D.; GIMENO, E.J.; BODEGA, J.J.; GARDEY, P.; ISEAS, F.B.; GIANNITTI, F. Enzootic calcinosis in horses grazing Solanum glaucophyllum in Argentina. Journal of Veterinary Diagnostic Investigation, v.30, n.2,p.286-289, 2018. OPEN ACCESS. Article history: First Published December 4, 2017.| Biblioteca(s): INIA La Estanzuela. |
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| 3. | | VERDES, J. M.; MÁRQUEZ, M.; CALLIARI, A.; BATES, D.; MORAÑA, J. A.; GIMENO, E. J.; ODRIOZOLA, E.; GIANNITTI, F.; GUERRERO, F.; FIDALGO, L. E.; PUMAROLA, M. A novel pathogenic mechanism for cerebellar lesions produced by Solanum bonariense in cattle. (Full Scientific Report) Journal of Veterinary Diagnostic Investigation, 2015, v.27 (3): 278-286. Article history: First Published April 21, 2015.| Biblioteca(s): INIA Las Brujas. |
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 | Acceso al texto completo restringido a Biblioteca INIA Tacuarembó. Por información adicional contacte bibliotb@tb.inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Tacuarembó. |
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Fecha actual : |
01/09/2020 |
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Actualizado : |
01/09/2020 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
MACHADO, M.; CASTRO, M.B; GIMENO, E.J.; BARROS, S.S.; RIET-CORREA, F. |
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Afiliación : |
MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARCIO B. CASTRO, Laboratorio de Patologia Veterinaria, Universidade de Brasília, Brasília, Brazil; EDUARDO J. GIMENO, Faculdad de Ciencias Veterinarias, National University of La Plata, Argentina; SEVERO S. BARROS, Laboratorio de Patologia Veterinaria, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Enzootic calcinosis in ruminants: A review. |
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Fecha de publicación : |
2020 |
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Fuente / Imprenta : |
Toxicon, 2020, volumen 187, Pages 1-9. Doi: https://doi.org/10.1016/j.toxicon.2020.08.009 |
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DOI : |
10.1016/j.toxicon.2020.08.009 |
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Idioma : |
Inglés |
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Contenido : |
ABSTRACT: Enzootic calcinosis (EC), is a chronic disease, caused by toxic plants, which has mainly affected ruminants for more than 100 years. It is characterized by a soft tissue calcification, hypercalcemia, hyperphosphatemia, hypoparathiroidism, hypercalcitoninism, osteonecrosis, and osteopetrosis. The toxic compound reported in some of these plants are 1,25(OH)2D3 glycosides. Characterization of calcinogenic principles were performed with Solanum glaucophyllum, Trisetum flavescens, Cestrum diurnum, and Stenotaphrum secundatum. Other plant species involved in EC are: Nierembergia rivularis, Nierembergia veitchii, Solanum torvum, and Solanum stuckertii. Clinical and pathological findings are well characterized. We present different aspects of the pathogenic mechanism of EC, including genetic modulation, expression of bone proteins, cellular de-differentiation of arterial smooth muscle cells, phenotypic changes, production of a calcifiable matrix, and modulation of the calcium and phosphorus balance. The use of comparative pathology can bring significant advances in the understanding of the pathogenic mechanism. In this review we present a broad approach to the different aspects of intoxication: history of EC on different continents; plant species, distribution and morphology; toxic principle; pathogenesis; epidemiology; clinical signs; diagnosis; and control and prophylaxis. |
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Palabras claves : |
CALCINOGENIC PLANTS; CALCINOSIS ENZOÓTICA; ENZOOTIC CALCINOSIS; INTOXICACIÓN; PATHOGENESIS; PLANTAS TÓXICAS; RUMIANTES; VITAMIN D; VITAMINA D. |
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Asunto categoría : |
L01 Ganadería |
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Marc : |
LEADER 02226naa a2200289 a 4500
001 1061290
005 2020-09-01
008 2020 bl uuuu u00u1 u #d
024 7 $a10.1016/j.toxicon.2020.08.009$2DOI
100 1 $aMACHADO, M.
245 $aEnzootic calcinosis in ruminants$bA review.$h[electronic resource]
260 $c2020
520 $aABSTRACT: Enzootic calcinosis (EC), is a chronic disease, caused by toxic plants, which has mainly affected ruminants for more than 100 years. It is characterized by a soft tissue calcification, hypercalcemia, hyperphosphatemia, hypoparathiroidism, hypercalcitoninism, osteonecrosis, and osteopetrosis. The toxic compound reported in some of these plants are 1,25(OH)2D3 glycosides. Characterization of calcinogenic principles were performed with Solanum glaucophyllum, Trisetum flavescens, Cestrum diurnum, and Stenotaphrum secundatum. Other plant species involved in EC are: Nierembergia rivularis, Nierembergia veitchii, Solanum torvum, and Solanum stuckertii. Clinical and pathological findings are well characterized. We present different aspects of the pathogenic mechanism of EC, including genetic modulation, expression of bone proteins, cellular de-differentiation of arterial smooth muscle cells, phenotypic changes, production of a calcifiable matrix, and modulation of the calcium and phosphorus balance. The use of comparative pathology can bring significant advances in the understanding of the pathogenic mechanism. In this review we present a broad approach to the different aspects of intoxication: history of EC on different continents; plant species, distribution and morphology; toxic principle; pathogenesis; epidemiology; clinical signs; diagnosis; and control and prophylaxis.
653 $aCALCINOGENIC PLANTS
653 $aCALCINOSIS ENZOÓTICA
653 $aENZOOTIC CALCINOSIS
653 $aINTOXICACIÓN
653 $aPATHOGENESIS
653 $aPLANTAS TÓXICAS
653 $aRUMIANTES
653 $aVITAMIN D
653 $aVITAMINA D
700 1 $aCASTRO, M.B
700 1 $aGIMENO, E.J.
700 1 $aBARROS, S.S.
700 1 $aRIET-CORREA, F.
773 $tToxicon, 2020, volumen 187, Pages 1-9. Doi: https://doi.org/10.1016/j.toxicon.2020.08.009
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